Custom Peptides
Cayman Chemical Ro 106-9920 10mg
A phospholipid containing the medium-chain (120) lauric acid inserted at the sn-1 and sn-2 positions commonly used in the generation of micelles liposomes and other types of artificial membranes
Cayman Chemical CysmethynIl 10mg
An alkaloid with anticancer and antioxidant activities binds to GSH and inhibits the GSH-GSTP1 protein-protein interaction reduces the viability of A549 and NCI H460 cells (IC50s 14.91 and 13.72 UM respectively) reduces tumor growth in an A549 mouse xenograft model at 2.5 and 5 mg/kg twice per week reduces plasma glucose levels as well as levels of plasma and pancreatic TBARS and lipid hydroperoxides in a rat model of streptozotocin-induced diabetes
Cayman Chemical MeOSucAlaAlaProValAMC 10mg
A saturated fatty acid incorporated into myristoyl-CoA and transferred by N-myristoyltransferase to the N-terminal glycine of certain proteins
Cayman Chemical AtglIstatIn 10mg
A Nampt inhibitor (IC50 25 nM) selectively inhibits Nampt over NMN/NaMN adenylyltransferase 1 at 10 UM reduces NAD levels in and is cytotoxic to HeLa cells at 100 nM decreases ATP levels in C666-1 and FaDu cells in a time-dependent manner at 10 and 20 nM respectively reduces tumor growth in MCF-7 breast cancer and NYH small cell lung cancer mouse xenograft models at 100 and 250 mg/kg per week
Cayman Chemical CostunolIde 10mg
Immunogen Synthetic peptide corresponding to amino acids 38-70 from human podoplanin Host Rat Species Reactivity ( ) Human Cross Reactivity ( ) Podoplanin Applications FC WB MW ~42 kDa
Cayman Chemical AM2201 8quInolnyl caramI 10mg
A potent inhibitor of SGLT2 (Kis 12.4 and 26 nM for human and rat SGLT2 respectively) selective for SGLT2 over SGLT1 (Kis 4520 and 997 nM for human and rat SGLT1 respectively)
Cayman Chemical CucurbItacIn B 10mg
A potent inhibitor of the non-receptor tyrosine kinases Abl and Src as well as other members of the Src family inhibits Abl Src and Lck with IC50 values of 0.05 0.5 and 0.4 nM respectively has potential therapeutic value in some forms of cancer and fibrotic disease
Cayman Chemical tculta Blnco Nobltn 10mg
The dextrorotary isomer of L-DOPA converted to L-DOPA via sequential oxidation and transamination which are mediated by DAAO and DOPA transaminase respectively in rat kidney homogenates reduces the number of dopaminergic neurons in primary rat embryonic mesencephalic cultures in a concentration-dependent manner increases striatal dopamine levels in rats at 200 Ug/animal induces contralateral turns in a rat model of 6-OHDA-induced Parkinsons disease at 20 mg/kg
Cayman Chemical 20 S-GInsenosIde Rg3 10mg
A DPP-4 inhibitor (IC50 18 nM) selective for DPP-4 over DPP-8 (IC50 48 UM) as well as several other peptidases improves glucose tolerance in insulin-resistant Zucker fatty and high-fat diet fed rats as well as ob/ob and high-fat diet fed mice reduces hyperglycemia in mice fed a high-fat diet with streptozotocin-induced diabetes
Cayman Chemical 1 2DIpalmItoylsnglycero3 10mg
A more stable form of (–)-blebbistatin the active form of blebbistatin has the same stereochemistry as the active (–)-blebbistatin enantiomer
Cayman Chemical AcetylCoenzyme AsodIM sal 10mg
An Oct4-activating compound which activates expression through the Oct4 gene promoter at 1 M enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells from embryonic fibroblasts expressing Oct4 with Sox2 Klf4 and c-Myc
Cayman Chemical MelItracenhydrochlorIde 10mg
An aminobutyl derivative of ADP has been used in the synthesis of quantum dots in ADP-specific TR-FRET assays
Cayman Chemical FexapotIdetrIfluoroacetAT 10mg
A long-chain acylcarnitine and GlyT2 inhibitor (IC50 340 nM) selective for GlyT2 over GlyT1 (IC50 10000 nM) plasma levels are increased in patients with chronic kidney disease or end-stage renal disease receiving incident hemodialysis and these are associated with cardiovascular mortality
Cayman Chemical TaccalonlIde AJ 10mg
A CP4H1 inhibitor (IC50 4 UM) selective for CP4H1 over HIF-PH2 at 10 UM