Custom Peptides
Cayman Chemical 10Chloroestra1 4dIen3 17 10mg
A sterone ERα agonist; increases reporter gene expression in S. cerevisiae (EC50 = 0.36 nM for the human receptor); an aromatase inhibitor (IC50 = 2.4 µM)
Cayman Chemical CnrtInIbhydrochlorIde 10mg
An irreversible quinazoline-based HER family tyrosine kinase inhibitor with IC50 values of 0.8, 19, and 7 nM for blocking in vitro activity of EGFR, HER2, and HER4, respectively; inhibits the proliferation of various tumor cells
Cayman Chemical AlexIdInhydrochlorIde 10mg
An alkyl bis(biguanide) antiseptic which kills plaque forming microorganisms; binds to LPS and LTA and inhibits fungal phospholipase B (IC50 ~ 250 nM); inhibits the mitochondrial phosphatase PTPMT1 (IC50 = 1.08 μM, in vitro) and induces apoptosis in cancer cell lines (ED50 = 1.8-2.6 μM)
Cayman Chemical NorursodeoxycholIc AcId 10mg
A bile acid; is secreted in an unchanged form, as trihydroxy derivatives, or as sulfate or glucuronide conjugates; decreases serum levels of ALT and alkaline phosphatase, periductal fibrosis, and hepatic hydroxyproline content in an Mdr2-/- mouse model of sclerosing cholangitis at 0.5% w/w in the diet
Cayman Chemical JWH 018 5hydroxyIndl meta 10mg
A major urinary metabolite of JWH 018; intended for research and forensic applications
Cayman Chemical 2EthylethcathInonhydrochl 10mg
A substituted cathinone with potential for abuse; intended for forensic and research applications
Cayman Chemical OmadacyclIn 10mg
An aminomethylcycline antibiotic; active against tetracycline-susceptible and -resistant strains of S. aureus, E. faecalis, E. faecium, S. pneumoniae, and E. coli, as well as β-hemolytic streptococci (MICs = ≤0.06-2 UG/ml); efficacious in mouse models of systemic infection with tetracycline-sensitive and -resistant strains of S. pneumoniae, S. aureus, or E. coli (ED50s = 0.3-3.34 mg/kg)
Cayman Chemical 5-APBhydrochlorIde 10mg
An analytical reference standard categorized as a benzofuran; a metabolite of 5-MAPB; a potential metabolite of 5-EAPB; intended for research and forensic applications
Cayman Chemical MetaprIston 10mg
An active metabolite of mifepristone; an antagonist of human glucocorticoid and progesterone receptors with relative affinities of 61 and 21%, respectively, compared to mifepristone; decreases the proliferation of A375 and B16/F10 cells (IC50s = 57.4 and 75.8 µM, respectively); induces cell-cycle arrest at the G1 phase in B16/F10 cells at 80 µM; decreases the number of lung metastases in a B16/F10 murine model of lung metastasis at 2.5, 10, and 50 mg/kg per day
Cayman Chemical 1Naphthyl 3 5DNItrobenzAT 10mg
A dual 5-LO and mPGES-1 inhibitor (IC50s = 1 and 3.6 µM, respectively)
Cayman Chemical TetrahydrocurcumIn 10mg
A metabolite of curcumin with diverse biological activities; scavenges DPPH radicals in a cell-free assay (EC50 = 16.8 μM); inhibits LPS-induced increases in iNOS and COX-2 expression in RAW 264.7 cells at 50 µM; inhibits LPS-induced increases in TNF-α release at 100 µM; inhibits LPS-induced increases in NO production and IL-6 levels in a concentration-dependent manner; reduces carrageenan-induced paw edema in rats (ED50 = 20 mg/kg); reduces the formation of neocapillaries and decreases microvascular density as well as VEGF, VEGFR2, and HIF-1α expression in a CaSki cervical cancer nude mouse xenograft model at 100, 300, and 500 mg/kg
Cayman Chemical 7fluoro TryptamInhydrochl 10mg
A tryptamine derivative that potentially agonizes 5-HT serotonin receptors; intended for research and forensic applications